A Mexican gang headed by vicious Pedro terrorizes the land between New Mexico and Arizona. Jeff a youth whose father has been killed by Pedro seeks revenge.
The story follows a band of former Confederate soldiers who were part of a cavalry unit. Their commander, Graff, had once been a heroic and staunch supporter of the Southern cause, but after losing his family, he became coldhearted and ruthless. His second-in-command is Eustis, whom Graff has trained on the strategies of leadership and combat command.
The stooges go out west for Shemp's health and get mixed up with some bad guys. The villains have locked up the Arizona Kid and their leader plans to marry his girl, Nell. The boys help the Arizona Kid escape and he rides to fetch the Cavalry. Somehow, the stooges manage to defeat the bad guys before the Cavalry arrives.
Jeff Scott is sent to investigate problems with wagon trains attempting to make the journey to Oregon. Sam Morgan has sent his henchmen, under lead-henchman Bull Bragg, to stop the wagon trains in order to maintain control of the fur trade in the area.
Red Reagan, and two companions, Brooks and Mathis, lose their way while on a prospecting trip in the mountains. Fortunately they come to an Indian camp where they get food and water, and So-Jun-Wah a beauteous Indian maid, shows them the trail to the settlement.
Hardy ranch owner Delia Jamieson hires John Trent as her foreman after he befriends her niece Martha. Jeff Carey, jealous of Trent's friendship with Martha, plants some stolen gold in his room and reveals this act to Delia, who visits Trent privately. Trent tries to tell Delia of his love for Martha, but she misunderstands him, thinking he is in love with her. When Delia does understand, however, she sends Martha away and orders the boys to whip Trent. She repents in time, sacrificing herself for her niece's happiness.
Lt. Col. Kirby Yorke is posted on the Texas frontier to defend settlers against depredations of marauding Apaches. Col. Yorke is under considerable stress by a serious shortage of troops of his command. Tension is added when Yorke's son (whom he hasn't seen in fifteen years), Trooper Jeff Yorke, is one of 18 recruits sent to the regiment.
During a cattle drive, Don McGow leaves the herd in charge of his younger brother and rides off. When the herd is reported stolen he blames himself and goes in search of the thieves.
A discouraged prospector is about to give up his search when he hears his two little children praying, "Please, God, help papa find gold." Their faith gives him new hope and their prayer is efficacious, for he does find it and so stakes the claim, intending to register it at his earliest opportunity. Meanwhile "Faro Kate" and her gambler husband ride by the claim and jump it, the husband urging Kate to go to the Claim Office and register it. When the prospector returns to his "diggings" he finds the gambler in possession and in a struggle the prospector falls and is hurt. The prospector's wife, arriving at the claim, realizes she must win the race to the Claim Office.
When Mort loses his and Ken's money at poker, Goss gets him to rob the stage. He is captured, identified by his palomino horse. Ken tries to clear him by robbing a stage while riding a palomino, but he also gets caught.
After her outlaw husband returns home shot with eight bullets and barely alive, Jane reluctantly reaches out to an ex-lover who she hasn't seen in over ten years to help her defend her farm when the time comes that her husband's gang eventually tracks him down to finish the job.
Michael, a half-breed Indian, is forced off a wagon train by scout Michael. Seeking revenge, he murders the wife of a college professor, kidnaps her baby daughter, and raises her as his own.
In the 1870s, a young Harvard dropout seeks his destiny out West by tying his fate to a team of buffalo hunters led by a man named Miller. Together, they embark on a harrowing journey risking life and sanity.