Byron Turner, a 15-year-old runaway from the Eatondale Orphan Asylum, receives a ride into the rural Missouri town of Delphi with rich land-owner Tobias Brown.
Fighter "Scotty" McQuade, contender for the light-heavyweight championship of the Pacific Coast,after being duped by his manager Ted Todd and fight-promoter Lew Slater, is disgusted with the fight game and decides to go back to punching cattle. He gets a job on the ranch owned by Colonel Hayden, where he once again encounters Slater, who has a crooked deal going that will cause Hayden to lose his ranch. With the aid of the Colonel's daughter, Betty Rose, and his pal "Frozen-Face" Cohen, McQuade breaks jail on a framed charge and puts an end to Slater's crooked dealings.
Chet Kasedon is after the Indians hidden gold mine but Chief Moya will not reveal it's location. He has also hired mining engineers Gale and Mortimer to locate the mine. When Gale sees Kasedon's cruelty to Moya, he switches sides.
A cowboy whose sister has been murdered by a gang of vicious outlaws seeks his revenge. But a venerable old lawman is about to teach the vigilante a lesson about taking the law into one's own hands.
Gangster Chandler and his accomplice Tracy arrive at a dude ranch. Cowboy Kentucky arrives at the same time. When Tracy double-crosses his boss and has the stage robbed, Kentucky finds the outlaws and brings them in. Tracy frames him for the murder of the driver but his pal Cactus gets him out of jail. He returns just as Chandler shoots Tracy and Kentucky finds himself arrested for another murder.
In his first starring Western for RKO, young Tim Holt must not only carry on his father's freight business but also hunt down his murderer. A certain Matt Gardner wants to corner the freight business to Pecos and persuades young Zack Sibley's wagon master to switch sides. Zack also earns the enmity of Gardner's son Coe, who takes umbrage to the youngster's flirtation with pretty Helen Lee. It all comes to a head during a food shortage in Pecos, a near-disaster that persuades the wagon master to switch sides once again. When the dust settles, Zack learns that old man Gardner is actually Carl Anderson, the man who murdered his father.
Colonel William Cody, alias Buffalo Bill, intends to put an end to the dishonest relations between a gang of white swindlers and the Indian, Yellow Hand. So he goes to the chief of Yellow Hand's tribe, Wise Fox, and tries to convince him to sign a peace treaty with the Federal troops. In order to avoid this, Yellow Hand abducts Wise Fox's daughter, pretending that the soldiers have done it.
Roy is a Confederate officer stationed in Missouri during the Civil War. He must put an end to outlaw gangs working under the pretense of service to the Confederacy.
Don Juan, the governor of a Mexican province, arrests Manuel, the fiancé of the beautiful heiress, Virginia. When Quintana frees Manuel, Don Juan kidnaps Virginia to force her hand in marriage. The ceremony is interrupted in a violent battle.
When John Barrabbee's plane makes an emergency landing, he wanders off and joins Roy's cattle drive. Later he learns he was killed when his plane resumed its flight and crashed. He also learns his daughter is going to sell his ranch and marry a man he dislikes. So he gives Roy a job on the ranch and sends him off to see if he can prevent both of these events while he remains in hiding. Written by Maurice VanAuken Western girl moves east and influenced badly by her snobby fiance. She returns to sell her deceased father's ranch. The father isn't really dead, though; he's hoping that his friend Roy can restore the girl's western values. Songs include "New Moon Over Nevada," "A Cowboy has to Yodel in the Morning," and "The Harum Scarum Baron of the Harmonium." Written by Ed Stephan
Bespectacled pistolero Stan Ross comes to Canyon City and becomes involved with two feuding factions, after a clerk has been killed by the banker Jefferson during a botched holdup, while robbing his own bank.
Sent to investigate a payroll robbery, Marshall Rocky meets his old friends Ken, Eddie, and Max. He has the serial numbers and when Pop puts on his medicine show they get one of the bills. This enables Ken to see through Sorrell's scheme that threw the blame on an innocent rancher and he sets out to prove it. Written by Maurice Van Auken
To get the three needed business men to visit the Stevens mine, Roy stages a ride with the Vacaros and has them as honored guests. Seeing a chance to make a lot of money, gangster Harmon joins the ride and then has his men kidnap the three. Having filmed a fake holdup earlier, he uses the film to convince the Sheriff that Roy and the boys were the Kidnapers.
When Peaceful Patton goes to work at the Martini ranch he is mistaken for the notorious outlaw the Hard Hombre. This enables him to force the ranchers to divide up the water rights. But he is in trouble when his mother arrives and exposes the hoax.
Scully has forced Joe Collins who works on the Garcia ranch to give him information so his men can steal the family jewels. But the Rough Riders are on the job. Buck poses as a wanted outlaw to get into the gang, Tim as a cattle buyer, and Sandy is collecting information as the saloon janitor. As usual they pretend not to know each other. Written by Maurice Van Auken